Microsoft spotlights Paige's year-old PRISM2 model trained on 2.3 million pathology slides
The model pairs digitized slides with clinical reports, but its benchmark results remain research evidence rather than clinical validation.
By Ryan Merket · Published · Updated
Primary source: Microsoft Research on X
Why it matters
PRISM2 shows pathology AI moving toward general models that accept clinical questions, while Tempus ownership gives Paige's research a route into a larger oncology platform.
Microsoft Research on August 4th drew fresh attention to PRISM2, a multimodal pathology model that Paige and Microsoft researchers first detailed in 2025. The model processes whole-slide tissue images and answers diagnostic questions in natural language, an approach its developers say can match or exceed narrower cancer-detection systems on several benchmarks.…
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