a16z's Fabrizio Serafini seeks startups building computer-use agents
The investor wants agents that finish business workflows inside software companies already use, a problem his August research says depends on reliability beyond model scores.
By Ryan Merket · Published
Primary source: X
Why it matters
Computer-use agents can reach work trapped behind interfaces without APIs, but enterprise adoption depends on dependable completion, verification and exception handling. Serafini's request points to that application layer as a target for a16z deal flow.
Fabrizio Serafini, an investment partner at Andreessen Horowitz focused on AI applications, is asking founders to bring him computer-use agents that can complete business tasks inside existing software. In a post on X on October 15th, Serafini described employees moving information between systems as a "human API" and called for agents that companies can trust to do real work at scale.